Basic Science News at Duke School of Medicine

Using Gene Therapy to Treat Brain Disease

Doug Marchuk, PhD, James B. Duke Distinguished Professor of Molecular Genetics and Microbiology, and Aravind Asokan, PhD, professor in surgery, have been awarded a three-year $1.9 million grant from the Department of Defense to develop less invasive treatment options for familial cerebral cavernous malformations (CCM).

Scientists Unlock Secrets of Gut Bacteria Linked to Heart Health

Scientists at Duke University School of Medicine are the first to decode the genetic makeup of Akkermansia, a gut bacterium that could help manage cholesterol levels and be used as a next-generation probiotic.  

Akkermansia thrives in the mucus layer of the intestine and has a knack for breaking down a type of sugary protein called mucin. This unique skill could be important for our health.